Protein Details: Aquaporin FA-CHIP

Protein ID

ICDB_Pro_0571

Protein Name

Aquaporin FA-CHIP

Gene Name

AQPA

Organism

Pelophylax lessonae (Pool frog) (Rana lessonae)

Length

272 amino acids

AlphaFoldDB

AF-P50501-F1-model_v4.pdb

Function

Forms a water-specific channel.

Sequence

MASEFKKKAFWRAVIAEFLAMILFVFISIGAALGFNFPIEEKANQTVGRSQDIVKVSLAFGISIATMAQSVGHVSGAHLNPAVTLGCLLSCQISILKAVMYIIAQCLGAVVATAILSGITSGLENNSLGLNGLSPGVSAGQGLGVEILVTFQLVLCVVAVTDRRRHDVSGSVPLAIGLSVALGHLIAIDYTGCGMNPARSFGSAVLTKNFTYHWIFWVGPMIGGAAAAIIYDFILAPRTSDLTDRMKVWTNGQVEEYELDGDDNTRVEMKPK

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

SITE 193: "Hg(2+)-sensitive residue"

Disease

Location

DOI ID

10.1016/0005-2736(94)90155-4